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Narcan is now available over-the-counter

By September 6, 2023May 21st, 2025No Comments

Thank you to The Washington Post for including MATTERS’ Chief Medical Officer, Dr. Joshua Lynch, in the discussion around naloxone (Narcan) being approved as an over-the-counter medication.

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External News: Narcan is now for sale without a prescription. Here’s what to know.

By David Ovalle

Narcan, the nasal spray that reverses opioid overdoses, is hitting store shelves this month for the first time as an over-the-counter medication — a milestone in the fight against the nation’s overdose crisis.

Manufacturer Emergent BioSolutions said last week that it has shipped hundreds of thousands of the two-spray kits, at a suggested retail price of $44.99. Major retailers such as CVS, Rite Aid, Walgreens and Walmart say the kits will be available on shelves in coming days. Companies are also selling the sprays online.

Narcan is a nasal spray version of naloxone, the opioid antidote credited with saving countless lives during the nation’s overdose crisis. More than 110,000 people are believed to have died of drug poisonings last year, more than two-thirds of them from synthetic opioids such as fentanyl. Prescription Narcan is widely used, carried by paramedics and police officers, distributed by groups that work on the streets to reduce the dangers of an increasingly toxic drug supply, and stocked in libraries, schools and even vending machines.

The Food and Drug Administration in March approved Narcan for over-the-counter use, a measure that advocates hope will expand its use by positioning the spray in supermarkets, corner stores and gas stations — and have it stored in first-aid kits or with families worried teens might overdose on counterfeit pills laced with fentanyl.

How does Narcan work?

Naloxone reverses the effects of opioids in the brain, restoring slowed or halted breathing. Narcan is not habit-forming — and is safe to use even in someone who has fallen unconscious but who turns out not to be overdosing on an opioid, said Joshua J. Lynch, associate professor of emergency and addiction medicine at the University at Buffalo.

Don’t test the spray first, Lynch said. “Giving the full vial into someone’s nose — and calling 911 right away — is the best practice,” he said.

Image developed by MATTERS

How expensive is Narcan?

Public health experts have long been concerned that over-the-counter Narcan will be too expensive for regular drug users — who are most at risk of overdosing. Still, over-the-counter Narcan for about $45 is an option for people who feel uncomfortable getting the medication from harm-reduction organizations, said Hansel E. Tookes III, an infectious-disease doctor at the University of Miami Miller School of Medicine.

“Of course, I would prefer that the Narcan were cheaper, but $45 to save a human life is a fantastic step in increasing access to lifesaving overdose prevention,” said Tookes, who founded the IDEA Exchange, a Miami program that exchanges used syringes for sterile ones and distributes naloxone to users on the streets.

Most states have used a system that allows Narcan to be dispensed by pharmacists without having to get an individual prescription from a doctor. Narcan going over-the-counter will make it easier to distribute in states with pharmacy restrictions, and advocates believe it will normalize use across a broad spectrum of U.S. society.

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